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Jerome H Check Selected Research

Mifepristone (RU 486)

12/2021New Insights as to Why Progesterone Receptor Modulators, such as Mifepristone, Seem to Be More Effective in Treating Cancers that Are Devoid of the Classical Nuclear Progesterone Receptor.
4/2021Palliative Benefits of Oral Mifepristone for the Treatment of Metastatic Fibroblastic Osteosarcoma.
12/2020Treatment With Mifepristone Allows a Patient With End-stage Pancreatic Cancer in Hospice on a Morphine Drip to Restore a Decent Quality of Life.
7/2019Therapy Aimed to Suppress the Production of the Immunosuppressive Protein Progesterone Induced Blocking Factor (PIBF) May Provide Palliation and/or Increased Longevity for Patients With a Variety of Different Advanced Cancers - A Review.
4/2019Mifepristone Extends Both Length and Quality of Life in a Patient With Advanced Non-small Cell Lung Cancer that Has Progressed Despite Chemotherapy and a Check-point Inhibitor.
12/2016Long-term High-quality Survival with Single-agent Mifepristone Treatment Despite Advanced Cancer.
5/2014Evidence that Mifepristone, a progesterone receptor antagonist, can cross the blood brain barrier and provide palliative benefits for glioblastoma multiforme grade IV.
5/2014Mifepristone causing complete remission of rapidly advancing leukemia with measurement of progesterone-induced blocking factor.
12/2010Progesterone receptor antagonist therapy has therapeutic potential even in cancer restricted to males as evidenced from murine testicular and prostate cancer studies.
2/2010Efficacy of the progesterone receptor antagonist mifepristone for palliative therapy of patients with a variety of advanced cancer types.
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Jerome H Check Research Topics

Disease

15Neoplasms (Cancer)
12/2021 - 05/2009
5Leukemia
05/2014 - 08/2007
4Lung Neoplasms (Lung Cancer)
04/2019 - 01/2010
3Infertility (Sterility)
02/2016 - 05/2003
3Spontaneous Abortion (Miscarriage)
09/2013 - 08/2009
2Pain (Aches)
12/2020 - 08/2004
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2019 - 12/2016
2Colonic Neoplasms (Colon Cancer)
02/2010 - 05/2009
1Osteosarcoma (Osteogenic Sarcoma)
04/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
12/2020
1Chronic Obstructive Pulmonary Disease (COPD)
04/2019
1Leiomyoma (Uterine Fibroids)
05/2017
1Leiomyosarcoma
05/2017
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
12/2016
1Renal Cell Carcinoma (Grawitz Tumor)
12/2016
1Brain Neoplasms (Brain Tumor)
05/2014
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
05/2014
1Glioblastoma (Glioblastoma Multiforme)
05/2014
1Habitual Abortion (Recurrent Miscarriage)
09/2013
1Thrombosis (Thrombus)
04/2012
1Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
04/2012
1Ulcerative Colitis
03/2011
1Crohn Disease (Crohn's Disease)
12/2010
1Testicular Neoplasms (Testicular Cancer)
12/2010
1Hemorrhage
12/2010
1Breast Neoplasms (Breast Cancer)
12/2010
1Prostatic Neoplasms (Prostate Cancer)
12/2010
1Lymphoma (Lymphomas)
08/2009
1Adenocarcinoma
05/2009
1Neoplasm Metastasis (Metastasis)
05/2009
1Endometriosis
05/2009
1Infections
08/2007

Drug/Important Bio-Agent (IBA)

14Progesterone Receptors (Progesterone Receptor)IBA
12/2021 - 05/2009
14Mifepristone (RU 486)FDA Link
12/2021 - 08/2007
13ProgesteroneFDA LinkGeneric
12/2021 - 08/2007
10Proteins (Proteins, Gene)FDA Link
12/2021 - 08/2007
7blocking factorIBA
12/2021 - 08/2007
2Pharmaceutical PreparationsIBA
12/2020 - 12/2016
2Immunologic Factors (Immunomodulators)IBA
09/2013 - 08/2007
2Sympathomimetics (Sympathomimetic Amines)IBA
03/2011 - 12/2010
1AntigensIBA
11/2021
1Morphine (MS Contin)FDA LinkGeneric
12/2020
1Nuclear Proteins (Protein, Nuclear)IBA
07/2019
1NivolumabIBA
04/2019
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
05/2017
1Monoclonal AntibodiesIBA
05/2017
1Protein Isoforms (Isoforms)IBA
05/2017
1DiureticsIBA
12/2016
1Investigational DrugsIBA
12/2016
1Hormones (Hormone)IBA
12/2016
1Progesterone CongenersIBA
02/2016
1DydrogesteroneFDA Link
09/2013
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
04/2012
1Therapeutic UsesIBA
04/2012
1Heparin (Liquaemin)FDA LinkGeneric
04/2012
1Dextroamphetamine (Dexedrine)FDA LinkGeneric
03/2011
1AminesIBA
03/2011
1Messenger RNA (mRNA)IBA
01/2010
1Biomarkers (Surrogate Marker)IBA
05/2009
1Lipopolysaccharide ReceptorsIBA
08/2007
1Antimicrobial PeptidesIBA
08/2007
1Estradiol (Delestrogen)FDA LinkGeneric
08/2004

Therapy/Procedure

11Therapeutics
04/2021 - 05/2003
4Drug Therapy (Chemotherapy)
04/2021 - 02/2010
2Palliative Care (Palliative Therapy)
05/2014 - 02/2010
1Radiotherapy
04/2021
1Nephrectomy
12/2016
1Immunotherapy
05/2009